{"id":5744,"date":"2021-10-09T22:12:17","date_gmt":"2021-10-09T22:12:17","guid":{"rendered":"https:\/\/activepharma.ru\/?post_type=product&#038;p=5744"},"modified":"2021-10-09T22:15:57","modified_gmt":"2021-10-09T22:15:57","slug":"s-adenosyl-methionine-sam-e","status":"publish","type":"product","link":"https:\/\/activepharma.ru\/ru\/product\/s-adenosyl-methionine-sam-e\/","title":{"rendered":"S-\u0430\u0434\u0435\u043d\u043e\u0437\u0438\u043b\u043c\u0435\u0442\u0438\u043e\u043d\u0438\u043d (SAM-e)"},"content":{"rendered":"<p>S-Adenosyl methionine (SAM-e) is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the liver. More than 40 methyl transfers from SAM-e are known, to various substrates such as nucleic acids, proteins, lipids, and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase.<\/p>\n<p>In bacteria, SAM-e is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM-e serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation immune response amino acid metabolism transsulfuration, and more. In plants, SAM-e is crucial to the biosynthesis of ethylene, an important plant hormone, and signaling molecule.<\/p>","protected":false},"excerpt":{"rendered":"<p>Meropenem is an intravenous \u03b2-lactam antibiotic used to treat a variety of bacterial infections. Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax. Meropenem usually results in bacterial death by blocking their ability to make a cell wall. It is more resistant to breakdown by \u03b2-lactamase producing bacteria.<\/p>\n<table class=\"woocommerce-product-attributes shop_attributes\">\n<tbody>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_cas\">\n<th class=\"woocommerce-product-attributes-item__label\">\u041a\u0410\u0421<\/th>\n<td class=\"woocommerce-product-attributes-item__value\">29908-03-0<\/td>\n<\/tr>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_formula\">\n<th class=\"woocommerce-product-attributes-item__label\">\u0424\u041e\u0420\u041c\u0423\u041b\u0410<\/th>\n<td class=\"woocommerce-product-attributes-item__value\">C15H22N6O5S<\/td>\n<\/tr>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_min-order-quantity-moq\">\n<th class=\"woocommerce-product-attributes-item__label\">\u041c\u0418\u041d. \u041a\u041e\u041b\u0418\u0427\u0415\u0421\u0422\u0412\u041e \u0417\u0410\u041a\u0410\u0417\u0410 (MOQ)<\/th>\n<td class=\"woocommerce-product-attributes-item__value\"><\/td>\n<\/tr>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pharmacopoeia\">\n<th class=\"woocommerce-product-attributes-item__label\">\u0424\u0410\u0420\u041c\u0410\u041a\u041e\u041f\u0415\u0419\u042f<\/th>\n<td class=\"woocommerce-product-attributes-item__value\">BP\/USP<\/td>\n<\/tr>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_appearance\">\n<th class=\"woocommerce-product-attributes-item__label\">APPEARANCE<\/th>\n<td class=\"woocommerce-product-attributes-item__value\"><\/td>\n<\/tr>\n<tr class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_melting-point\">\n<th class=\"woocommerce-product-attributes-item__label\">Melting point<\/th>\n<td class=\"woocommerce-product-attributes-item__value\">326.8 \u00b0C (620.2 \u00b0F)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"featured_media":5745,"template":"","meta":[],"product_cat":[15,63],"product_tag":[],"class_list":{"0":"post-5744","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","5":"hentry","6":"product_cat-apis","7":"product_cat-special-offers","9":"entry","10":"has-media","11":"owp-thumbs-layout-horizontal","12":"owp-btn-normal","13":"owp-tabs-layout-horizontal","14":"has-no-thumbnails","15":"has-product-nav","16":"circle-sale"},"_links":{"self":[{"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/product\/5744","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/media\/5745"}],"wp:attachment":[{"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/media?parent=5744"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/product_cat?post=5744"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/activepharma.ru\/ru\/wp-json\/wp\/v2\/product_tag?post=5744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}